个人邮箱：chemlxc@163.com；QQ: 171399079
刘西成，男，山东潍坊人，工学博士，副教授。主要从事无机化学、中级无机化学和无机化学实验的讲授工作；现主持山东省自然科学基金面上项目一项，近五年在Inorganic Chemistry，Inorganic Chemistry Frontiers，Dalton Transactions，Dyes and Pigments，Joural of Inorganic Biochemistry，Journal of Materials Chemistry C等国内外期刊上发表论文40余篇。
教育及工作经历：
2012/9 - 2016/6，天津大学，化工学院，工学博士
2002/9 - 2005/7，曲阜师范大学，化学院，理学硕士
1998/9 - 2002/7，曲阜师范大学，化学系，理学学士
研究方向：
小分子空穴传输材料的合成及其光电应用；
有机金属抗癌配合物的设计及诊疗一体化研究；
每年招收硕士1-2名、科研训练本科生8-10人、本科毕业设计学生8-10人。
硕士招生专业：无机化学/有机化学/应用化工/化学生物学;
欢迎有理想、有追求的有志青年报考！
主持或参加科研项目：
[1] 山东省自然科学基金面上项目：溶酶体靶向铁-铱异核金属席夫碱类抗癌体系的构建及机理研究（ZR2020MB102），2021.01~2023.12；主持。
[2] 山东省高等学校科技计划项目：聚集诱导发光金属铱四苯乙烯抗癌体系的构建及其抗癌机理研究（J18KA082），2018.6~2021.5；主持。
[3] 国家自然科学基金面上项目：基于双模激发联动干预功能性分子探针的ROS&AOS协同应激微环境分析与评价（22174090），2022.01-2025.12；参与。
[4] 国家重点研发计划：“印刷OLED显示关键材料与器件技术”(2016YFB0401300)；2016~2021年；参与。
[5] 国家高技术研究发展计划（863计划）：“柔性AMOLED显示材料产业化关键技术研究”（2015AA033402）；2015~2017年；参与。
指导大学生获奖及科研训练情况：
[1] 国家级大学生创新创业训练计划项目：含三苯胺基团环铱配合物的合成及抗癌性能研究（201710446042），唐艳华等（优秀结题）。
[2] 国家级大学生创新创业训练计划项目：三苯胺修饰的荧光型金属铱(III)双聚体的合成及抗肿瘤应用（S202010446011），姚美美等（已结题）。
[3] 省级大学生创新创业训练计划项目：溶酶体靶向金属铱香豆素抗癌体系的构建（S201910446046），2019.10-2021.5；张蕾等（已结题）。
[4] 省级大学生创新创业训练计划项目：脂溶性/水溶性调控的铱(III)配合物的设计及抗癌应用，2023.10-2025.05；李光晓等（在研）
[5] 校级大学生创新创业训练计划项目：铁-铱混合金属配合物抗癌体系的构建及生物性能研究（2018A043），2018.10 ~ 2020.5；指导（已结题）。
[6] 校级优秀本科毕业论文：唐艳华（2019年）；王子涵（2023年）。
[7] 山东省第十八届“挑战杯”大学生课外学术科技作品竞赛（自然科学类）二等奖（王子涵等）。
[8] “建行杯”第九届山东省“互联网+”大学生创新创业大赛 铜奖（董瑞箫等）。
[9] 曲阜师范大学第十八届“挑战杯”课外学术科技作品竞赛 特等奖（王子涵等）。
[10] 曲阜师范大学第九届“互联网+”大学生创新创业大赛 金奖（董瑞箫等）。
奖励情况:
2019年度山东省高等学校科学技术奖 叁等奖（第二位）
曲阜师范大学2019年青年教师教学比赛 校级二等奖
授权专利：
[1] 刘西成，刘哲，邵明晓，张莹，谢瑶琪，一种溶酶体靶向的荧光型金属铱双聚体及其制备方法和应用，申请号：202010111378.4，公布号：CN 111217732 A
[2] 刘西成，刘哲，刘聪，赵潇涵，郑梦霄，一种香豆素修饰的荧光型环铱(III)配合物及其制备方法和应用，申请号 202010625405 .X，公布号：CN 111646966 A
[3] 刘西成，邵明晓，刘哲，王丽艳，王子涵，一种金属铱-二茂铁席夫碱类配合物及其制备方法，申请号 ZL202110410038.6，公布号CN 113134964B
[4] 刘西成，王丽艳，刘哲，吕澳，李光晓，王佳丽，一种高荧光量子产率的半三明治结构铱吡啶配合物及其制备方法和应用，申请号 202211088251.0，公布号：CN 115385968B
[5] 刘西成，刘哲，李翘楚，陈光，孙心卓，任雪艳，一种具有AIE特性的有机锡-四苯乙烯酰腙化合物及其制备方法和应用，申请号 202210549409.3，公布号：CN 114835744B
代表性文章：
2024年度
[1] Xicheng Liu*, Ao Lv, Pei Zhang, Jiaying Chang, Ruixiao Dong, Mengxian Liu, Jiayi Liu, Xiaoqing Huang, Xiang-Ai Yuan and Zhe Liu*, The anticancer application of half-sandwich iridium(III) ferrocene-thiosemicarbazide Schiff base complexes, Dalton Transactions, 2024, 53, 552-563.
[2] Xicheng Liu*, Yiwei Sun, Qiaochu Li, Pei Zhang, Rui Tao, Jiaying Chang, Shuyu Zhang, Yingying Zhang, Yumeng Zhang, Xiang-Ai Yuan, Zhe Liu*, Organotin(IV)- tetraphenylethylene acylhydrazone compounds with aggregation-induced emission property and application in anticancer therapy, Dyes and Pigments, 2024, 223, 111963.
2023年度
[1] Liyan Wang, Xicheng Liu*, Yuting Wu, Xian He, Xiaohui Guo, Wenshan Gao, Lin Tan, Xiang-Ai Yuan, Jinfeng Liu, and Zhe Liu*, In Vitro and In Vivo Antitumor Assay of Mitochondrially Targeted Fluorescent Half-Sandwich Iridium(III) Pyridine Complexes, Inorganic Chemistry, 2023, 62, 3395–3408.
[2] Xicheng Liu*,1, Zihan Wang1, Xinru Zhang, Xiaocai Lv, Yong Sun, Ruixiao Dong, Guangxiao Li, Xueyan Ren, Zhongyin Ji, Xiang-Ai Yuan, Zhe Liu*, Configurationally regulated half-sandwich iridium(III)-ferrocene heteronuclear metal complexes: Potential anticancer agents, Journal of Inorganic Biochemistry 2023, 249, 112393.
[3] Jinfeng Liu*, Yuting Wu a, Ge Yang, Zhe Liu*, Xicheng Liu*, Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay, Journal of Inorganic Biochemistry, 2023, 239, 112069.
[4] Xiangdong He, Mengke Xu, Xicheng Liu,* and Yihong Wang*, A Novel Immunogenic Cell Death Inducer Based on Bimetallic Ferrocene Substituted Organotin Complexes, ChemistrySelect, 2023, 8, e202300464.
2022年度
[1] Qiaochu Li , Mingxiao Shao , Weiguang Ran, Xinzhuo Sun, Huiying Liu, Qi Wang, Xicheng Liu*, Laijin Tian, Guang Chen, Zhe Liu*, An AIE-featured triphenyltin(IV)-triphenylamine acylhydrazone compound and anticancer application, Dyes and Pigments, 2022, 201, 110231
[2] Ruixi Xu, Yuting Wu, Zhe Liu*, Jinfeng Liu and Xicheng Liu*, Lysosomal Targeted Cyclometallic Iridium(Ⅲ) Salicylaldehyde-Coumarin Schiff Base Complexes and Anticancer Application, Frontiers in Chemistry, 2022, 10, 906954
[3] Yuting Wu, Jinfeng Liu* , Mingxiao Shao , Pei Zhang, Shaohua Song, Ge Yang, Xicheng Liu*, Zhe Liu*, Cyclometalated iridium(III) dithioformic acid complexes as mitochondria-targeted imaging and anticancer agents, Journal of Inorganic Biochemistry 2022, 233, 111855
[4] Zihan Wang, Zexuan Lv, Xicheng Liu*, Yuting Wu, Jiaying Chang, Ruixiao Dong, Caiyue Li, Xiang-Ai Yuan, Zhe Liu*, Anticancer application of ferrocene appended configuration-regulated half-sandwich iridium(III) pyridine complexes, Journal of Inorganic Biochemistry 2022, 237, 112010
2021年度
[1] Mingxiao Shao,† Meimei Yao,† Xicheng Liu*, Chao Gao, Weiyan Liu, Jinghang Guo, Jiawen Zong, Xinzhuo Sun, and Zhe Liu*, In Vitro and In Vivo of Triphenylamine-Appended Fluorescent HalfSandwich Iridium(III) Thiosemicarbazones Antitumor Complexes, Inorganic Chemistry, 2021, 60, 17063−17073.
[2] Liyan Wang, Chenyang Huang, Fenglian Hu, Wen Cui, Yiqing Li, Jingwen Li, Jiawen Zong, Xicheng Liu*, Xiang-Ai Yuan and Zhe Liu*, Preparation and antitumor application of N-phenylcarbazole/triphenylamine-modified fluorescent half-sandwich iridium(III) Schiff base complexes, Dalton Transactions, 2021, 50, 15888.
[3] Xicheng Liu*, Mingxiao Shao, Congcong Liang, Jinghang Guo, Guangxuan Wang, Xiang-Ai Yuan, Zhihong Jing, Laijin Tian, Zhe Liu*, Preparation and bioactivity of iridium(III) phenanthroline complexes with halide ions and pyridine leaving groups, ChemBioChem, 2021, 22, 557-564.
2020年度
[1] Shujiao Chen, Xicheng Liu*, Xingxing Ge, Qinghui Wang, Yaoqi Xie, Yingying Hao, Ying Zhang, Lei Zhang, Wenjing Shang, Zhe Liu*, Lysosome-targeted iridium(III) compounds with pyridine-triphenylamine Schiff base ligands: Syntheses, antitumor application and mechanism, Inorganic Chemistry Frontiers, 2020, 7, 91–100.
[2] Xicheng Liu*, Shujiao Chen, Xingxing Ge, Ying Zhang, Yaoqi Xie, Yingying Hao, Daiqun Wu, Jinmin Zhao, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Dual functions of Iridium(III) 2-phenylpyridine complexes: metastasis inhibition and lysosomal damage, Joural of Inorganic Biochemistry, 2020, 205, 110983
[3] Bin Wang, Xicheng Liu, Peiwei Gong, Xingxing Ge, Zhe Liu and Jinmao You, Fluorescent COFs with a highly conjugated structure for visual drug loading and responsive release, Chemical Communications, 2020, 56, 519-522.
[4] Cong Liu, Xicheng Liu*, Xingxing Ge, Qinghui Wang, Lei Zhang, Wenjing Shang, Yue Zhang, XiangAi Yuan, Laijin Tian, Zhe Liu*, Jinmao You, Fluorescent iridium(III) coumarin-salicylaldehyde Schiff base compounds as Lysosome-Targeted antitumor agents, Dalton Transactions, 2020, 49, 5988–5998
[5] Xicheng Liu, Yali Han, Xingxing Ge and Zhe Liu, Imidazole and Benzimidazole Modified Half-Sandwich IridiumIII N-Heterocyclic Carbene Complexes: Synthesis, Anticancer Application, and Organelle Targeting, Frontiers in Chemistry, 2020, 8, 182
[6] Lexing Chen, Zhengwei Wang, Tongguang Qiu, Ruikun Sun, Zhiyuan Zhao, Laijin Tian*, Xicheng Liu*，Synthesis, structural characterization and properties of triorganotin complexes of Schiff base derived from 3-aminobenzoic acid and salicylaldehyde or 2,4-pentanedione，Applied Organometallic Chemistry, 2020, 34: e5790
[7] Shujiao Chen, Xicheng Liu*, Jie Huang*, Xingxing Ge, Qinghui Wang, Meimei Yao, Yue Shao, Tong Liu, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*，Triphenylamine/carbazole-modified Ruthenium(II) Schiff base compounds: Synthesis, biological activity and organelle targeting，Dalton Transactions, 2020, 49, 8774–8784.
[8] Mingxiao Shao, Xicheng Liu*, Yiwei Sun, Shuaihua Dou, Qi Chen, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Preparation and anticancer mechanism of configuration-controlled Fe(II)-Ir(III) heteronuclear metal complexes, Dalton Transactions, 2020, 49, 12599–12609.
2019年度
[1] Xicheng Liu*, Xiangdong He, Xiaojing Zhang, Yongling Wang, Jiaying Liu, Xiujuan Hao, Yue Zhang, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*, Synthesis and Antineoplastic Applications of TPE Appended Organometallic Iridium(III) Complexes, ChemBioChem, 2019, 20, 2767 – 2776
[2] Xicheng Liu*, Hailong Hao, Xingxing Ge, Xiangdong He, Yifei Liu, Yan Wang, Haojie Wang, Mingxiao Shao, Zhihong Jing, Laijin, Tian, Zhe Liu*, Triphenylamine-appended cyclometallated iridium(III) complexes: Preparation, photophysical properties and application in biology/luminescence imaging, Joural of Inorganic Biochemistry, 2019, 199, 110757.
[3] Xicheng Liu*, Yanhua Tang, Xiangdong He, Xingxing Ge, Jiao Liu, Xiaoyu Meng, Mingxiao Shao, Yingmin Jin, Laijin Tian*, Zhe Liu*, Triphenyltin(IV) acylhydrazone compounds: Synthesis, structure and bioactivity, Journal of Inorganic Biochemistry, 2019, 191, 194–202.
[4] Liu Xi-Cheng, Liu Xin-Yu, Zhou Ping, Li Jin-Jie, Tian Hao-Ze, Li Xiang-Gao*, Synthesis, Characterization and Properties of Bipolar Triphenylamine Charge Transport Materials, Chinese Joural of Structural Chemistry, 2019, 38, 533-540.
[5] Xiangdong He, Xicheng Liu*, Yanhua Tang, Jiuyao Du, Meng Tian, Zhishan Xu, Xinyu Liu, Zhe Liu*, Half-sandwich Iridium(III) complexes with triphenylamine-substituted dipyridine frameworks and bioactivity applications, Dyes and Pigments, 2019, 160, 217–226.
[6] Xingxing Ge, Shujiao Chen, Xicheng Liu*, Qinghui Wang, Lijun Gao, Chengfeng Zhao, Lei Zhang, Mingxiao Shao, Xiang-Ai Yuan, Laijin Tian, Zhe Liu*，Ferrocene-Appended Iridium(III) Complexes: Configuration Regulation, Anticancer Application and Mechanism Research, Inorganic Chemistry, 2019, 58, 14175−14184.
[7] Juanjuan Li, Xicheng Liu*, Haifeng Zhang, Xingxing Ge, Yanhua Tang, Zhishan Xu, Laijin Tian, Xiangai Yuan, Xudong Mao, and Zhe Liu*, Ferrocenyl-Triphenyltin Complexes as Lysosome-Targeted Imaging and Anticancer Agents, Inorgnic Chemistry, 2019, 58, 1710−1718.
[8] Shujiao Chen, Xicheng Liu*, Zhenzhen Tian, Xingxing Ge, Hailong Hao, Yingying Hao, Ying Zhang, Yaoqi Xie, Laijin Tian, Zhe Liu*，Triphenylamine and carbazole-modified iridiumIII 2-phenylpyridine complexes: Synthesis, anticaner application and targeted research, Applied Organometallic Chemistry, 2019, e5053
[9] Xingxing Ge, Xicheng Liu*, Zhenzhen Tian, Shujiao Chen, Xinyu Liu, Lihua Guo, Peiwei Gong, Baoping Ling, Xiang-Ai Yuan, Zhe Liu*, Half-sandwich Ruthenium(II) complexes with triphenylamine modified dipyridine skeleton and application in biology/luminescence imaging, Applied Organometallic Chemistry, 2019, e5171.
[10] Hailong Hao, Xicheng Liu*, Xingxing Ge, Yao Zhao, Xue Tian, Ting Ren, Yan Wang, Chengfeng Zhao, Zhe Liu, Half-sandwich iridium(III) complexes with α-picolinic acid frameworks and antitumor applications, Journal of Inorganic Biochemistry, 2019, 192, 52–61.
2018年度
[1] Xiangdong He, Meng Tian, Xicheng Liu*, Yanhua Tang, Chang Fang Shao, Peiwei Gong, Jinfeng Liu, Shumiao Zhang, Lihua Guo, and Zhe Liu*, Triphenylamine-Appended Half-Sandwich Iridium(III) Complexes and Their Biological Applications, Chemistry-An Asian Joural, 2018, 13, 1500-1509.
[2] Yali Han, Zhenzhen Tian, Shumiao Zhang, Xicheng Liu*, Juanjuan Li, Yanru Li, Yi Liu, Min Gao, Zhe Liu*, Half-sandwich IridiumIII N-heterocyclic carbene antitumor complexes and biological applications, Journal of Inorganic Biochemistry, 2018, 189, 163-171.
[3] Yali Han, Xicheng Liu, Zhenzhen Tian, Xingxing Ge, Juanjuan Li, Min Gao, Yanru Li, Yi Liu, Zhe Liu*, Half-sandwich Iridium(III) Benzimidazole-Appended Imidazolium Based N-heterocyclic Carbene Complexes and Antitumor Application, Chemistry-An Asian Joural, 2018, 13, 3697–3705.
2017年以前
[1] Xicheng Liu, Fei Zhang, Zhe Liu, Yin Xiao, Shirong Wang and Xianggao Li*, Dopant-free and low-cost molecular ‘‘bee’’ hole-transporting materials for efficient and stable perovskite solar cells, Journal of Materials Chemistry C, 2017, 5, 11429-11435.
[2] Liu Xicheng, Zhu Lifeng, Zhang Fei, You Jing, Xiao Yin, Li Dongmei, Wang Shirong, Meng Qingbo, Li Xianggao, Stable non-doping perovskite solar cells based on hydrophobic triphenylamine hole-transporting materials, Energy Technology, 2017, 5, 312 – 320.
[3] Liu Xicheng, You Jing, Xiao Yin, Wang Shirong, Gao Wenzheng, Peng Junbiao and Li Xianggao, Film-forming hole transporting materials for high brightness flexible organic light-emitting diodes, Dyes and Pigments, 2016, 125: 36-43.
[4] Liu Xicheng, Liang Junfei, You Jing, Ying Lei, Xiao Yin, Wang Shirong and Li Xianggao, Small molecular hole-transporting and emitting materials for hole-only green organic light-emitting devices, Dyes and Pigments, 2016, 131: 41-48.
[5] Zhang Fei#, Liu Xicheng#, Yi Chenyi, Bi Dongqin, Luo Jingshan,Wang Shirong*, Li Xianggao*, Xiao Yin, Zakeeruddin Shaik Mohammed*, Grätzel Michael*, Dopant-Free Donor (D)-p-D-p-D Conjugated HoleTransport Materials for Efficient and Stable Perovskite Solar Cells, ChemSusChem, 2016, 9, 2578–2585.
